The Placebo Effect, Part 2 - Why Clinical Trials Need Placebo Control

The Placebo Effect, Part 2 - Why Clinical Trials Need Placebo Control

“Placebo controls: without them, you know almost nothing”

0:00 Introduction

0:28 “Double-blind placebo controlled trial”

4:17 The Restasis story. Recommended video: The Dry Eye Debate: How Effective is Allergan’s Restasis and Should We Be Paying for It?

7:36 Would you approve this drug?

8:07 Side effects: When the drug makes you worse, and can a placebo make you worse?

9:35 Without a placebo arm in the clinical trial, you’ll never know how often improvement is due to the drug (not the placebo effect) and how often worsening is due to the drug (not a natural worsening of the condition)

9:52 How does this connect to biologic eye drops?

10:20 “But I’m sure my biologic eye drop is working”